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Double Positive CD4(+)CD8(+) T Cells Are Enriched in Urological Cancers and Favor T Helper-2 Polarization

The immune system plays a central role in cancer development, showing both anti-tumor and pro-tumor activities depending on the immune cell subsets and the disease context. While CD8 T cells are associated with a favorable outcome in most cancers, only T helper type 1 (Th1) CD4 T cells play a protec...

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Detalles Bibliográficos
Autores principales:	Bohner, Perrine, Chevalier, Mathieu F., Cesson, Valérie, Rodrigues-Dias, Sonia-Christina, Dartiguenave, Florence, Burruni, Rodolfo, Tawadros, Thomas, Valerio, Massimo, Lucca, Ilaria, Nardelli-Haefliger, Denise, Jichlinski, Patrice, Derré, Laurent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450069/ https://www.ncbi.nlm.nih.gov/pubmed/30984190 http://dx.doi.org/10.3389/fimmu.2019.00622

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