Prime-Boost Immunizations with DNA, Modified Vaccinia Virus Ankara, and Protein-Based Vaccines Elicit Robust HIV-1 Tier 2 Neutralizing Antibodies against the CAP256 Superinfecting Virus

A vaccine regimen that elicits broadly neutralizing antibodies (bNAbs) is a major goal in HIV-1 vaccine research. In this study, we assessed the immunogenicity of the CAP256 superinfecting viral envelope (CAP256 SU) protein delivered by modified vaccinia virus Ankara (MVA) and DNA vaccines in differ...

Descripción completa

Detalles Bibliográficos
Autores principales: van Diepen, Michiel T., Chapman, Rosamund, Douglass, Nicola, Galant, Shireen, Moore, Penny L., Margolin, Emmanuel, Ximba, Phindile, Morris, Lynn, Rybicki, Edward P., Williamson, Anna-Lise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450106/
https://www.ncbi.nlm.nih.gov/pubmed/30760570
http://dx.doi.org/10.1128/JVI.02155-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450106/
https://www.ncbi.nlm.nih.gov/pubmed/30760570
http://dx.doi.org/10.1128/JVI.02155-18

Ejemplares similares