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NOP Receptor Agonist Ro 64-6198 Decreases Escalation of Cocaine Self-Administration in Rats Genetically Selected for Alcohol Preference

Cocaine dependence is a psychiatric condition for which effective medications are still lacking. Published data indicate that an increase in nociceptin/orphanin FQ (N/OFQ) transmission by NOP receptor activation attenuates cocaine-induced place conditioning and the locomotor sensitization effects of...

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Detalles Bibliográficos
Autores principales: Li, Hongwu, Scuppa, Giulia, Shen, Qianwei, Masi, Alessio, Nasuti, Cinzia, Cannella, Nazzareno, Ciccocioppo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450143/
https://www.ncbi.nlm.nih.gov/pubmed/30984046
http://dx.doi.org/10.3389/fpsyt.2019.00176