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Cross-Protective Potential and Protection-Relevant Immune Mechanisms of Whole Inactivated Influenza Virus Vaccines Are Determined by Adjuvants and Route of Immunization

Adjuvanted whole inactivated virus (WIV) influenza vaccines show promise as broadly protective influenza vaccine candidates. Using WIV as basis we assessed the relative efficacy of different adjuvants by carrying out a head-to-head comparison of the liposome-based adjuvants CAF01 and CAF09 and the p...

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Detalles Bibliográficos
Autores principales:	Bhide, Yoshita, Dong, Wei, Gribonika, Inta, Voshart, Daniëlle, Meijerhof, Tjarko, de Vries-Idema, Jacqueline, Norley, Stephen, Guilfoyle, Kate, Skeldon, Sarah, Engelhardt, Othmar G., Boon, Louis, Christensen, Dennis, Lycke, Nils, Huckriede, Anke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450434/ https://www.ncbi.nlm.nih.gov/pubmed/30984200 http://dx.doi.org/10.3389/fimmu.2019.00646

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