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Mapping of Dynamic Transcriptome Changes Associated With Silica-Triggered Autoimmune Pathogenesis in the Lupus-Prone NZBWF1 Mouse
Crystalline silica (cSiO(2)) is a widely recognized environmental trigger of autoimmune disease. In the lupus-prone female NZBWF1 mouse, airway exposure to cSiO(2) triggers pulmonary ectopic lymphoid neogenesis, systemic autoantibody elevation, and glomerulonephritis. Here we tested the hypothesis t...
Autores principales: | Bates, Melissa A., Benninghoff, Abby D., Gilley, Kristen N., Holian, Andrij, Harkema, Jack R., Pestka, James J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450439/ https://www.ncbi.nlm.nih.gov/pubmed/30984195 http://dx.doi.org/10.3389/fimmu.2019.00632 |
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