Stearoyl CoA Desaturase Is Essential for Regulation of Endoplasmic Reticulum Homeostasis and Tumor Growth in Glioblastoma Cancer Stem Cells

Inherent plasticity and various survival cues allow glioblastoma stem-like cells (GSCs) to survive and proliferate under intrinsic and extrinsic stress conditions. Here, we report that GSCs depend on the adaptive activation of ER stress and subsequent activation of lipogenesis and particularly stear...

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Detalles Bibliográficos
Autores principales: Pinkham, Kelsey, Park, David Jaehyun, Hashemiaghdam, Arsalan, Kirov, Aleksandar B., Adam, Isam, Rosiak, Kamila, da Hora, Cintia C., Teng, Jian, Cheah, Pike See, Carvalho, Litia, Ganguli-Indra, Gitali, Kelly, Avalon, Indra, Arup K., Badr, Christian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450460/
https://www.ncbi.nlm.nih.gov/pubmed/30930246
http://dx.doi.org/10.1016/j.stemcr.2019.02.012

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