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β-Adrenergic Receptor Stimulation and Alternans in the Border Zone of a Healed Infarct: An ex vivo Study and Computational Investigation of Arrhythmogenesis
Background: Following myocardial infarction (MI), the myocardium is prone to calcium-driven alternans, which typically precedes ventricular tachycardia and fibrillation. MI is also associated with remodeling of the sympathetic innervation in the infarct border zone, although how this influences arrh...
Autores principales: | Tomek, Jakub, Hao, Guoliang, Tomková, Markéta, Lewis, Andrew, Carr, Carolyn, Paterson, David J., Rodriguez, Blanca, Bub, Gil, Herring, Neil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450465/ https://www.ncbi.nlm.nih.gov/pubmed/30984029 http://dx.doi.org/10.3389/fphys.2019.00350 |
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