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Pseudomonas aeruginosa esterase PA2949, a bacterial homolog of the human membrane esterase ABHD6: expression, purification and crystallization
The human membrane-bound α/β-hydrolase domain 6 (ABHD6) protein modulates endocannabinoid signaling, which controls appetite, pain and learning, as well as being linked to Alzheimer’s and Parkinson’s diseases, through the degradation of the key lipid messenger 2-arachidonylglycerol (2-AG). This make...
Autores principales: | Bleffert, Florian, Granzin, Joachim, Gohlke, Holger, Batra-Safferling, Renu, Jaeger, Karl-Erich, Kovacic, Filip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450514/ https://www.ncbi.nlm.nih.gov/pubmed/30950828 http://dx.doi.org/10.1107/S2053230X19002152 |
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