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Substrate-analogue complex structure of Mycobacterium tuberculosis decaprenyl diphosphate synthase

Decaprenyl diphosphate synthase from Mycobacterium tuberculosis (MtDPPS, also known as Rv2361c) catalyzes the consecutive elongation of ω,E,Z-farnesyl diphosphate (EZ-FPP) by seven isoprene units by forming new cis double bonds. The protein folds into a butterfly-like homodimer like most other cis-t...

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Detalles Bibliográficos
Autores principales:	Ko, Tzu-Ping, Xiao, Xiansha, Guo, Rey-Ting, Huang, Jian-Wen, Liu, Weidong, Chen, Chun-Chi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2019
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450523/ https://www.ncbi.nlm.nih.gov/pubmed/30950820 http://dx.doi.org/10.1107/S2053230X19001213

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