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Antibody-mediated targeting of cleavage-specific OPN-T cell interactions
T cells are crucial players in obesity-mediated adipose tissue inflammation. We hypothesized that osteopontin (OPN), an inflammatory protein with enhanced activity when proteolytically cleaved, affects the number of viable T cells in adipose tissue and assessed inhibition of the interaction between...
Autores principales: | Wanko, Bettina, Tardelli, Matteo, Jürets, Alexander, Neuhofer, Angelika, Prager, Gerhard, Morser, John, Leung, Lawrence L., Staffler, Günther, Zeyda, Maximilian, Stulnig, Thomas M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450625/ https://www.ncbi.nlm.nih.gov/pubmed/30951532 http://dx.doi.org/10.1371/journal.pone.0214938 |
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