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The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification

Peg10 (paternally expressed gene 10) is an imprinted gene that is essential for placental development. It is thought to derive from a Ty3-gyspy LTR (long terminal repeat) retrotransposon and retains Gag and Pol-like domains. Here we show that the Gag domain of PEG10 can promote vesicle budding simil...

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Detalles Bibliográficos
Autores principales: Abed, Mona, Verschueren, Erik, Budayeva, Hanna, Liu, Peter, Kirkpatrick, Donald S., Reja, Rohit, Kummerfeld, Sarah K., Webster, Joshua D., Gierke, Sarah, Reichelt, Mike, Anderson, Keith R., Newman, Robert J., Roose-Girma, Merone, Modrusan, Zora, Pektas, Hazal, Maltepe, Emin, Newton, Kim, Dixit, Vishva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450627/
https://www.ncbi.nlm.nih.gov/pubmed/30951545
http://dx.doi.org/10.1371/journal.pone.0214110