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Plasma neurofilament light chain: A potential prognostic biomarker of dementia in adult Down syndrome patients

People with Down syndrome (DS) are at high risk of developing Alzheimer disease (AD) with aging. The diagnosis and treatment trials are hampered by a lack of reliable blood biomarkers. Plasma neurofilament light chain (NfL) is one of the established biomarkers of AD, suggesting that it may be useful...

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Detalles Bibliográficos
Autores principales:	Shinomoto, Makiko, Kasai, Takashi, Tatebe, Harutsugu, Kondo, Masaki, Ohmichi, Takuma, Morimoto, Masafumi, Chiyonobu, Tomohiro, Terada, Naoto, Allsop, David, Yokota, Isao, Mizuno, Toshiki, Tokuda, Takahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450630/ https://www.ncbi.nlm.nih.gov/pubmed/30951523 http://dx.doi.org/10.1371/journal.pone.0211575

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