Dynamic interplay between H-current and M-current controls motoneuron hyperexcitability in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a type of motor neuron disease (MND) in which humans lose motor functions due to progressive loss of motoneurons in the cortex, brainstem, and spinal cord. In patients and in animal models of MND it has been observed that there is a change in the properties of...

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Detalles Bibliográficos
Autores principales: Buskila, Yossi, Kékesi, Orsolya, Bellot-Saez, Alba, Seah, Winston, Berg, Tracey, Trpceski, Michael, Yerbury, Justin J., Ooi, Lezanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450866/
https://www.ncbi.nlm.nih.gov/pubmed/30952836
http://dx.doi.org/10.1038/s41419-019-1538-9

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