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A Tumor-Selective Monoclonal Antibody from Immunization with a Tumor-Associated Mucin Glycopeptide

We have previously studied the generation of immune responses after vaccination with tumor-associated carbohydrate antigen (TACA)-containing glycopeptides from the tandem repeat (TR) sequence of MUC4, an aberrantly expressed mucin in pancreatic adenocarcinomas. A specific lead antigen from that stud...

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Detalles Bibliográficos
Autores principales: Trabbic, Kevin R., Whalen, Kaitlyn, Abarca-Heideman, Karin, Xia, Li, Temme, J. Sebastian, Edmondson, Elijah F., Gildersleeve, Jeffrey C., Barchi, Joseph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450958/
https://www.ncbi.nlm.nih.gov/pubmed/30952968
http://dx.doi.org/10.1038/s41598-019-42076-2