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PCC0208027, a novel tyrosine kinase inhibitor, inhibits tumor growth of NSCLC by targeting EGFR and HER2 aberrations

PCC-0208027 is a novel tyrosine kinase inhibitor that has a strong inhibitory effect on epidermal growth factor receptor (EGFR)- or HER2-driven cancers. The aim is to assess the anti-tumor activity of PCC0208027 and related mechanisms in non-small cell lung cancer (NSCLC). We examined the activity o...

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Detalles Bibliográficos
Autores principales:	Dong, Qiuju, Yu, Pengfei, Ye, Liang, Zhang, Jianzhao, Wang, Hongbo, Zou, Fangxia, Tian, Jingwei, Kurihara, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451005/ https://www.ncbi.nlm.nih.gov/pubmed/30952931 http://dx.doi.org/10.1038/s41598-019-42245-3

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