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α-Synuclein-derived lipoparticles in the study of α-Synuclein amyloid fibril formation

Aggregation of the protein α-Synuclein (αSyn) is of great interest due to its involvement in the pathology of Parkinson’s disease. However, under in vitro conditions αSyn is very soluble and kinetically stable for extended time periods. As a result, most αSyn aggregation assays rely on conditions th...

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Detalles Bibliográficos
Autores principales: Falke, Marcel, Victor, Julian, Wördehoff, Michael M., Peduzzo, Alessia, Zhang, Tao, Schröder, Gunnar F., Buell, Alexander K., Hoyer, Wolfgang, Etzkorn, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451039/
https://www.ncbi.nlm.nih.gov/pubmed/30826264
http://dx.doi.org/10.1016/j.chemphyslip.2019.02.009

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