ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development

Stress hormones bind and activate the glucocorticoid receptor (GR) in many tissues including the brain. We identified arginine and glutamate rich 1 (ARGLU1) in a screen for new modulators of glucocorticoid signaling in the CNS. Biochemical studies show that the glutamate rich C-terminus of ARGLU1 co...

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Detalles Bibliográficos
Autores principales: Magomedova, Lilia, Tiefenbach, Jens, Zilberman, Emma, Le Billan, Florian, Voisin, Veronique, Saikali, Michael, Boivin, Vincent, Robitaille, Melanie, Gueroussov, Serge, Irimia, Manuel, Ray, Debashish, Patel, Rucha, Xu, ChangJiang, Jeyasuria, Pancharatnam, Bader, Gary D, Hughes, Timothy R, Morris, Quaid D, Scott, Michelle S, Krause, Henry, Angers, Stephane, Blencowe, Benjamin J, Cummins, Carolyn L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451108/
https://www.ncbi.nlm.nih.gov/pubmed/30698747
http://dx.doi.org/10.1093/nar/gkz010

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