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Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase

Pif1 is a multifunctional helicase and DNA processing enzyme that has roles in genome stability. The enzyme is conserved in eukaryotes and also found in some prokaryotes. The functions of human PIF1 (hPIF1) are also critical for survival of certain tumour cell lines during replication stress, making...

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Detalles Bibliográficos
Autores principales:	Dehghani-Tafti, Saba, Levdikov, Vladimir, Antson, Alfred A, Bax, Ben, Sanders, Cyril M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451128/ https://www.ncbi.nlm.nih.gov/pubmed/30698796 http://dx.doi.org/10.1093/nar/gkz028

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