The Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) Protocol: a prospective, multi-center, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial

BACKGROUND: Sepsis accounts for 30% to 50% of all in-hospital deaths in the United States. Other than antibiotics and source control, management strategies are largely supportive with fluid resuscitation and respiratory, renal, and circulatory support. Intravenous vitamin C in conjunction with thiam...

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Detalles Bibliográficos
Autores principales: Hager, David N., Hooper, Michael H., Bernard, Gordon R., Busse, Laurence W., Ely, E. Wesley, Fowler, Alpha A., Gaieski, David F., Hall, Alex, Hinson, Jeremiah S., Jackson, James C., Kelen, Gabor D., Levine, Mark, Lindsell, Christopher J., Malone, Richard E., McGlothlin, Anna, Rothman, Richard E., Viele, Kert, Wright, David W., Sevransky, Jonathan E., Martin, Greg S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451231/
https://www.ncbi.nlm.nih.gov/pubmed/30953543
http://dx.doi.org/10.1186/s13063-019-3254-2

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