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Sequence-dependent synergistic cytotoxicity of icotinib and pemetrexed in human lung cancer cell lines in vitro and in vivo

BACKGROUND: Recent Clinical trials of administration of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) in combination with standard first-line chemotherapy have failed to improve survival in patients with advanced NSCLC, However, the sequential treatment with EGFR-TKIs and c...

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Detalles Bibliográficos
Autores principales:	Liu, Tianze, Jin, Lizi, Lu, Wenjing, Gan, Hairun, Lin, Zhidong, Chen, Miao, Liu, Jiani, Zhang, Fan, Wang, Siyang, Zhang, Hongyu, Deng, Wuguo, Chen, Hongtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451286/ https://www.ncbi.nlm.nih.gov/pubmed/30953548 http://dx.doi.org/10.1186/s13046-019-1133-z

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