Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins

BACKGROUND: The mechanisms underpinning the regenerative capabilities of mesenchymal stem cells (MSC) were originally thought to reside in their ability to recognise damaged tissue and to differentiate into specific cell types that would replace defective cells. However, recent work has shown that m...

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Detalles Bibliográficos
Autores principales: Mitchell, Robert, Mellows, Ben, Sheard, Jonathan, Antonioli, Manuela, Kretz, Oliver, Chambers, David, Zeuner, Marie-Theres, Tomkins, James E., Denecke, Bernd, Musante, Luca, Joch, Barbara, Debacq-Chainiaux, Florence, Holthofer, Harry, Ray, Steve, Huber, Tobias B., Dengjel, Joern, De Coppi, Paolo, Widera, Darius, Patel, Ketan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451311/
https://www.ncbi.nlm.nih.gov/pubmed/30953537
http://dx.doi.org/10.1186/s13287-019-1213-1

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