Alteration of 28S rRNA 2′-O-methylation by etoposide correlates with decreased SMN phosphorylation and reduced Drosha levels

The most common types of modification in human rRNA are pseudouridylation and 2′-O ribose methylation. These modifications are performed by small nucleolar ribonucleoproteins (snoRNPs) which contain a guide RNA (snoRNA) that base pairs at specific sites within the rRNA to direct the modification. rR...

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Detalles Bibliográficos
Autores principales: Burke, Marilyn F., McLaurin, Douglas M., Logan, Madelyn K., Hebert, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451326/
https://www.ncbi.nlm.nih.gov/pubmed/30858166
http://dx.doi.org/10.1242/bio.041848

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