PRR14L mutations are associated with chromosome 22 acquired uniparental disomy, age related clonal hematopoiesis and myeloid neoplasia

Acquired uniparental disomy (aUPD, also known as copy-neutral loss of heterozygosity) is a common feature of cancer cells and characterized by extended tracts of somatically-acquired homozygosity without any concurrent loss or gain of genetic material. The presumed genetic targets of many regions of...

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Detalles Bibliográficos
Autores principales: Chase, Andrew, Pellagatti, Andrea, Singh, Shalini, Score, Joannah, Tapper, William J., Lin, Feng, Hoade, Yvette, Bryant, Catherine, Trim, Nicola, Yip, Bon Ham, Zoi, Katerina, Rasi, Chiara, Forsberg, Lars A., Dumanski, Jan P., Boultwood, Jacqueline, Cross, Nicholas C. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451636/
https://www.ncbi.nlm.nih.gov/pubmed/30573780
http://dx.doi.org/10.1038/s41375-018-0340-5

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