Breast cancer cells rely on environmental pyruvate to shape the metastatic niche

Extracellular matrix (ECM) is a major component of the local environment, i.e. the niche, that can determine cell behavior1. During metastatic growth, cancer cells shape the ECM of the metastatic niche by hydroxylating collagen to promote their own metastatic growth2, 3. However, only particular nut...

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Detalles Bibliográficos
Autores principales: Elia, Ilaria, Rossi, Matteo, Stegen, Steve, Broekaert, Dorien, Doglioni, Ginevra, van Gorsel, Marit, Boon, Ruben, Escalona-Noguero, Carmen, Torrekens, Sophie, Verfaillie, Catherine, Verbeken, Erik, Carmeliet, Geert, Fendt, Sarah-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451642/
https://www.ncbi.nlm.nih.gov/pubmed/30814728
http://dx.doi.org/10.1038/s41586-019-0977-x

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