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Inactivation of SAG or ROC1 E3 Ligase Inhibits Growth and Survival of Renal Cell Carcinoma Cells: Effect of BIM()

SAG (Sensitive to Apoptosis Gene) and ROC1 (Regulator of Cullin-1) are two family members of the RING component of CRL (Cullin RING ligase). Both members are essential for growth and survival of several types of human cancer cells; their role in renal cell carcinoma (RCC), however, remains elusive....

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Detalles Bibliográficos
Autores principales: Wang, Yu, Tan, Mingjia, Li, Hua, Li, Haomin, Sun, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451688/
https://www.ncbi.nlm.nih.gov/pubmed/30954776
http://dx.doi.org/10.1016/j.tranon.2019.03.002