Cargando…

Sex differences in [(11)C]ABP688 binding: a positron emission tomography study of mGlu5 receptors

PURPOSE: The purpose of this study was to assess, in a large sample of healthy young adults, sex differences in the binding potential of [(11)C]ABP688, a positron emission tomography (PET) tracer selective for the metabotropic glutamate type 5 (mGlu5) receptor. METHODS: High resolution [(11)C]ABP688...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smart, Kelly, Cox, Sylvia M. L., Scala, Stephanie G., Tippler, Maria, Jaworska, Natalia, Boivin, Michel, Séguin, Jean R., Benkelfat, Chawki, Leyton, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2019
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451701/ https://www.ncbi.nlm.nih.gov/pubmed/30627817 http://dx.doi.org/10.1007/s00259-018-4252-4

Ejemplares similares

mGlu5 receptor availability in youth at risk for addictions: effects of vulnerability traits and cannabis use
por: Cox, Sylvia M. L., et al.
Publicado: (2020)

Characterization of brain mGluR5 binding in a pilot study of late-life major depressive disorder using positron emission tomography and [(11)C]ABP688
por: DeLorenzo, C, et al.
Publicado: (2015)

Metabotropic Glutamate Receptor Type 5 (mGluR5) Cortical Abnormalities in Focal Cortical Dysplasia Identified In Vivo With [(11)C]ABP688 Positron-Emission Tomography (PET) Imaging
por: DuBois, Jonathan M., et al.
Publicado: (2016)

Structural insights into dimerization and activation of the mGlu2–mGlu3 and mGlu2–mGlu4 heterodimers
por: Wang, Xinwei, et al.
Publicado: (2023)

Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [(11)C]ABP688 and PET imaging study in depression
por: Esterlis, Irina, et al.
Publicado: (2017)

In Vivo Imaging of mGluR5 Changes during Epileptogenesis Using [(11)C]ABP688 PET in Pilocarpine-Induced Epilepsy Rat Model
por: Choi, Hongyoon, et al.
Publicado: (2014)

Imaging in vivo glutamate fluctuations with [(11)C]ABP688: a GLT-1 challenge with ceftriaxone
por: R Zimmer, Eduardo, et al.
Publicado: (2015)

Extra-striatal D(2/3) receptor availability in youth at risk for addiction
por: Jaworska, Natalia, et al.
Publicado: (2020)

mGluR5 binding changes during a mismatch negativity task in a multimodal protocol with [(11)C]ABP688 PET/MR-EEG
por: Régio Brambilla, Cláudia, et al.
Publicado: (2022)

Impact of framing scheme optimization and smoking status on binding potential analysis in dynamic PET with [(11)C]ABP688
por: Régio Brambilla, Cláudia, et al.
Publicado: (2023)

mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists
por: Zammataro, Magda, et al.
Publicado: (2011)

Allosteric Modulators for mGlu Receptors
por: Gasparini, F, et al.
Publicado: (2007)

Noninvasive Relative Quantification of [(11)C]ABP688 PET Imaging in Mice Versus an Input Function Measured Over an Arteriovenous Shunt
por: Verhaeghe, Jeroen, et al.
Publicado: (2018)

Acute Ketamine Infusion in Rat Does Not Affect In Vivo [(11)C]ABP688 Binding to Metabotropic Glutamate Receptor Subtype 5
por: Kosten, Lauren, et al.
Publicado: (2018)

Reduced uptake of [11C]‐ABP688, a PET tracer for metabolic glutamate receptor 5 in hippocampus and amygdala in Alzheimer’s dementia
por: Treyer, Valerie, et al.
Publicado: (2020)

Radiosynthesis and Evaluation of an (18)F-Labeled Positron Emission Tomography (PET) Radioligand for Metabotropic Glutamate Receptor Subtype 4 (mGlu(4))
por: Kil, Kun-Eek, et al.
Publicado: (2014)

Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice
por: Lane, Tracy A, et al.
Publicado: (2013)

Emotional Impairment and Persistent Upregulation of mGlu(5) Receptor following Morphine Abstinence: Implications of an mGlu(5)-MOPr Interaction
por: Zanos, Panos, et al.
Publicado: (2016)

mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors
por: Notartomaso, Serena, et al.
Publicado: (2018)

Is there a relation between novelty seeking, striatal dopamine release and frontal cortical thickness?
por: Jaworska, Natalia, et al.
Publicado: (2017)

Externalizing Risk Pathways for Adolescent Substance Use and Its Developmental Onset: A Canadian Birth Cohort Study: Trajectoires de comportements extériorisés et le risque pour l’initiation et l’usage de substances des adolescents : Une étude de cohorte de naissance canadienne
por: Cox, Sylvia Maria Leonarda, et al.
Publicado: (2021)

mGlu5 Receptor Functional Interactions and Addiction
por: Brown, Robyn M., et al.
Publicado: (2012)

mGlu(5) Positive Allosteric Modulators Facilitate Long-Term Potentiation via Disinhibition Mediated by mGlu(5)-Endocannabinoid Signaling
por: Xiang, Zixiu, et al.
Publicado: (2019)

Neurobiological Insights from mGlu Receptor Allosteric Modulation
por: O’Brien, Daniel E, et al.
Publicado: (2015)

Exploring the Activation Mechanism of the mGlu5 Transmembrane Domain
por: Lans, Isaias, et al.
Publicado: (2020)

Regulation and functional consequences of mGlu(4) RNA editing
por: Hofmann, Christopher S., et al.
Publicado: (2021)

Differential activity of mGlu(7) allosteric modulators provides evidence for mGlu(7/8) heterodimers at hippocampal Schaffer collateral-CA1 synapses
por: Lin, Xin, et al.
Publicado: (2022)

Function of mGlu1 receptors in the modulation of nociceptive processing in the thalamus()
por: Salt, T.E., et al.
Publicado: (2014)

Structural insights into the activation initiation of full-length mGlu1
por: Zhang, Jinyi, et al.
Publicado: (2020)

mGlu2 mechanism-based interventions to treat alcohol relapse
por: Vengeliene, Valentina, et al.
Publicado: (2022)

The role of thalamic group II mGlu receptors in health and disease
por: Copeland, Caroline S., et al.
Publicado: (2022)

Dopaminergic Plasticity in the Bilateral Hippocampus Following Threat Reversal in Humans
por: Lissemore, Jennifer I., et al.
Publicado: (2020)

Deletion of Metabotropic Glutamate Receptors 2 and 3 (mGlu2 & mGlu3) in Mice Disrupts Sleep and Wheel-Running Activity, and Increases the Sensitivity of the Circadian System to Light
por: Pritchett, David, et al.
Publicado: (2015)

A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding
por: García-Bea, Aintzane, et al.
Publicado: (2017)

Activation of mGlu3 Receptors Stimulates the Production of GDNF in Striatal Neurons
por: Battaglia, Giuseppe, et al.
Publicado: (2009)

Role of the G Protein-Coupled Receptor, mGlu(1), in Melanoma Development
por: Wangari-Talbot, Janet, et al.
Publicado: (2010)

Preclinical and translational studies of fenobam, an mGlu5 NAM, for the treatment of pain
por: Gereau IV, Robert W, et al.
Publicado: (2014)

Phasic and Tonic mGlu7 Receptor Activity Modulates the Thalamocortical Network
por: Tassin, Valériane, et al.
Publicado: (2016)

Place field stability requires the metabotropic glutamate receptor, mGlu5
por: Zhang, Sijie, et al.
Publicado: (2014)

Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective
por: Dalton, James A.R., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_fuletchm3m5n77v7kq3vruk2d9