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Dihydrotanshinone-Induced NOX5 Activation Inhibits Breast Cancer Stem Cell through the ROS/Stat3 Signaling Pathway

Cancer stem cells (CSCs) are known to mediate metastasis and recurrence and are therefore a promising therapeutic target. In this study, we found that dihydrotanshinone (DHTS) inhibits CSC formation. DHTS inhibited mammosphere formation in a dose-dependent manner and showed significant tumor growth...

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Detalles Bibliográficos
Autores principales:	Kim, Su-Lim, Choi, Hack Sun, Kim, Ji-Hyang, Jeong, Dong Kee, Kim, Ki-Seok, Lee, Dong-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451810/ https://www.ncbi.nlm.nih.gov/pubmed/31019654 http://dx.doi.org/10.1155/2019/9296439

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