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Comparative In Vitro Activities of New Antibiotics for the Treatment of Skin Infections
Bacterial skin infections result in significant morbidity and have contributed to enhanced health-care resource utilization. The problem is heightened by emerging antimicrobial resistance. Multiple novel agents active against resistant pathogens that cause skin infections—including dalbavancin, tedi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451995/ https://www.ncbi.nlm.nih.gov/pubmed/30957168 http://dx.doi.org/10.1093/cid/ciz003 |
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author | Shortridge, Dee Flamm, Robert K |
author_facet | Shortridge, Dee Flamm, Robert K |
author_sort | Shortridge, Dee |
collection | PubMed |
description | Bacterial skin infections result in significant morbidity and have contributed to enhanced health-care resource utilization. The problem is heightened by emerging antimicrobial resistance. Multiple novel agents active against resistant pathogens that cause skin infections—including dalbavancin, tedizolid phosphate, oritavancin, and delafloxacin—have been approved over the past 5 years. Common features of these agents include gram-positive activity and favorable safety. Of these agents, delafloxacin is unique in being active against both gram-positive and gram-negative pathogens that cause skin infections, including those resistant to other antimicrobial agents. It is, therefore, an effective option for the treatment of skin infections. |
format | Online Article Text |
id | pubmed-6451995 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-64519952019-04-11 Comparative In Vitro Activities of New Antibiotics for the Treatment of Skin Infections Shortridge, Dee Flamm, Robert K Clin Infect Dis Supplement Articles Bacterial skin infections result in significant morbidity and have contributed to enhanced health-care resource utilization. The problem is heightened by emerging antimicrobial resistance. Multiple novel agents active against resistant pathogens that cause skin infections—including dalbavancin, tedizolid phosphate, oritavancin, and delafloxacin—have been approved over the past 5 years. Common features of these agents include gram-positive activity and favorable safety. Of these agents, delafloxacin is unique in being active against both gram-positive and gram-negative pathogens that cause skin infections, including those resistant to other antimicrobial agents. It is, therefore, an effective option for the treatment of skin infections. Oxford University Press 2019-04-01 2019-04-08 /pmc/articles/PMC6451995/ /pubmed/30957168 http://dx.doi.org/10.1093/cid/ciz003 Text en © The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Supplement Articles Shortridge, Dee Flamm, Robert K Comparative In Vitro Activities of New Antibiotics for the Treatment of Skin Infections |
title | Comparative In Vitro Activities of New Antibiotics for the Treatment of Skin Infections |
title_full | Comparative In Vitro Activities of New Antibiotics for the Treatment of Skin Infections |
title_fullStr | Comparative In Vitro Activities of New Antibiotics for the Treatment of Skin Infections |
title_full_unstemmed | Comparative In Vitro Activities of New Antibiotics for the Treatment of Skin Infections |
title_short | Comparative In Vitro Activities of New Antibiotics for the Treatment of Skin Infections |
title_sort | comparative in vitro activities of new antibiotics for the treatment of skin infections |
topic | Supplement Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451995/ https://www.ncbi.nlm.nih.gov/pubmed/30957168 http://dx.doi.org/10.1093/cid/ciz003 |
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