Nebulised lipid–polymer hybrid nanoparticles for the delivery of a therapeutic anti-inflammatory microRNA to bronchial epithelial cells

Modulation of microRNAs (miRNAs), endogenous regulators of gene expression, is a promising strategy for tackling inflammatory lung diseases. In this proof-of-concept study, we tested delivery of miR-17 to bronchial epithelial cells (BECs) using nebulised lipid–polymer hybrid nanoparticles (LPNs). Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Vencken, Sebastian, Foged, Camilla, Ramsey, Joanne M., Sweeney, Louise, Cryan, Sally-Ann, MacLoughlin, Ronan J., Greene, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452044/
https://www.ncbi.nlm.nih.gov/pubmed/30972350
http://dx.doi.org/10.1183/23120541.00161-2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452044/
https://www.ncbi.nlm.nih.gov/pubmed/30972350
http://dx.doi.org/10.1183/23120541.00161-2018

Ejemplares similares