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Vancomycin-induced DRESS syndrome treated with systemic steroids in a 16-year-old male

This is a case report of a 16-year-old patient with DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) associated with vancomycin who improved with systemic steroid treatment. DRESS syndrome is a life-threatening disease process typically secondary to medications, such as anticon...

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Detalles Bibliográficos
Autores principales: Maldonado, Dylan, Lakhani, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452422/
https://www.ncbi.nlm.nih.gov/pubmed/31057800
http://dx.doi.org/10.1177/2050313X19841704
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author Maldonado, Dylan
Lakhani, Jay
author_facet Maldonado, Dylan
Lakhani, Jay
author_sort Maldonado, Dylan
collection PubMed
description This is a case report of a 16-year-old patient with DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) associated with vancomycin who improved with systemic steroid treatment. DRESS syndrome is a life-threatening disease process typically secondary to medications, such as anticonvulsants, sulfonamides, and allopurinol. Vancomycin has also been associated with this condition. Apart from discontinuation of the offending agent, there are no clear treatment guidelines, but reports of improvement with systemic corticosteroids are described. We present a case of a 16-year-old male who had been on vancomycin for greater than 4 weeks before developing symptoms consistent with the diagnosis of DRESS syndrome. Our patient demonstrated marked improvement with systemic corticosteroids.
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spelling pubmed-64524222019-05-03 Vancomycin-induced DRESS syndrome treated with systemic steroids in a 16-year-old male Maldonado, Dylan Lakhani, Jay SAGE Open Med Case Rep Case Report This is a case report of a 16-year-old patient with DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) associated with vancomycin who improved with systemic steroid treatment. DRESS syndrome is a life-threatening disease process typically secondary to medications, such as anticonvulsants, sulfonamides, and allopurinol. Vancomycin has also been associated with this condition. Apart from discontinuation of the offending agent, there are no clear treatment guidelines, but reports of improvement with systemic corticosteroids are described. We present a case of a 16-year-old male who had been on vancomycin for greater than 4 weeks before developing symptoms consistent with the diagnosis of DRESS syndrome. Our patient demonstrated marked improvement with systemic corticosteroids. SAGE Publications 2019-04-04 /pmc/articles/PMC6452422/ /pubmed/31057800 http://dx.doi.org/10.1177/2050313X19841704 Text en © The Author(s) 2019 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Maldonado, Dylan
Lakhani, Jay
Vancomycin-induced DRESS syndrome treated with systemic steroids in a 16-year-old male
title Vancomycin-induced DRESS syndrome treated with systemic steroids in a 16-year-old male
title_full Vancomycin-induced DRESS syndrome treated with systemic steroids in a 16-year-old male
title_fullStr Vancomycin-induced DRESS syndrome treated with systemic steroids in a 16-year-old male
title_full_unstemmed Vancomycin-induced DRESS syndrome treated with systemic steroids in a 16-year-old male
title_short Vancomycin-induced DRESS syndrome treated with systemic steroids in a 16-year-old male
title_sort vancomycin-induced dress syndrome treated with systemic steroids in a 16-year-old male
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452422/
https://www.ncbi.nlm.nih.gov/pubmed/31057800
http://dx.doi.org/10.1177/2050313X19841704
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