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A patient with neurofibromatosis type 1 presenting with bilateral frontal lobe infarctions following anterior communicating artery aneurysm rupture
Neurofibromatosis is a neurocutaneous genetic condition with dysplasia of the mesodermal and ectodermal tissues. Vascular abnormalities are well recognized in neurofibromatosis and cerebral aneurysms are rarely reported in literature. Here, we present a 20-year-old Sri Lankan female presented with h...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452425/ https://www.ncbi.nlm.nih.gov/pubmed/31057798 http://dx.doi.org/10.1177/2050313X19841151 |
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author | Herath, HMMTB Yogendranathan, Nilukshana Kulatunga, Aruna |
author_facet | Herath, HMMTB Yogendranathan, Nilukshana Kulatunga, Aruna |
author_sort | Herath, HMMTB |
collection | PubMed |
description | Neurofibromatosis is a neurocutaneous genetic condition with dysplasia of the mesodermal and ectodermal tissues. Vascular abnormalities are well recognized in neurofibromatosis and cerebral aneurysms are rarely reported in literature. Here, we present a 20-year-old Sri Lankan female presented with headache, altered personality, disinhibited behaviour, and urinary incontinence. On imaging, she was found to have infarctions of both frontal lobes and evidence of a ruptured anterior communicating artery aneurysm with a small subarachnoid haemorrhage. Another small middle cerebral artery aneurysm was also seen in the angiogram. She was managed conservatively and gradually recovered. Because aneurysms in neurofibromatosis are usually asymptomatic and as rupture of such an aneurysm is rare, regular vascular screening is not recommended to all patients with neurofibromatosis. This is the first case report in literature in which a patient with neurofibromatosis presented with infarctions of both frontal lobes due to rupture of an anterior communicating artery aneurysm. |
format | Online Article Text |
id | pubmed-6452425 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-64524252019-05-03 A patient with neurofibromatosis type 1 presenting with bilateral frontal lobe infarctions following anterior communicating artery aneurysm rupture Herath, HMMTB Yogendranathan, Nilukshana Kulatunga, Aruna SAGE Open Med Case Rep Case Report Neurofibromatosis is a neurocutaneous genetic condition with dysplasia of the mesodermal and ectodermal tissues. Vascular abnormalities are well recognized in neurofibromatosis and cerebral aneurysms are rarely reported in literature. Here, we present a 20-year-old Sri Lankan female presented with headache, altered personality, disinhibited behaviour, and urinary incontinence. On imaging, she was found to have infarctions of both frontal lobes and evidence of a ruptured anterior communicating artery aneurysm with a small subarachnoid haemorrhage. Another small middle cerebral artery aneurysm was also seen in the angiogram. She was managed conservatively and gradually recovered. Because aneurysms in neurofibromatosis are usually asymptomatic and as rupture of such an aneurysm is rare, regular vascular screening is not recommended to all patients with neurofibromatosis. This is the first case report in literature in which a patient with neurofibromatosis presented with infarctions of both frontal lobes due to rupture of an anterior communicating artery aneurysm. SAGE Publications 2019-04-04 /pmc/articles/PMC6452425/ /pubmed/31057798 http://dx.doi.org/10.1177/2050313X19841151 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Herath, HMMTB Yogendranathan, Nilukshana Kulatunga, Aruna A patient with neurofibromatosis type 1 presenting with bilateral frontal lobe infarctions following anterior communicating artery aneurysm rupture |
title | A patient with neurofibromatosis type 1 presenting with bilateral
frontal lobe infarctions following anterior communicating artery aneurysm
rupture |
title_full | A patient with neurofibromatosis type 1 presenting with bilateral
frontal lobe infarctions following anterior communicating artery aneurysm
rupture |
title_fullStr | A patient with neurofibromatosis type 1 presenting with bilateral
frontal lobe infarctions following anterior communicating artery aneurysm
rupture |
title_full_unstemmed | A patient with neurofibromatosis type 1 presenting with bilateral
frontal lobe infarctions following anterior communicating artery aneurysm
rupture |
title_short | A patient with neurofibromatosis type 1 presenting with bilateral
frontal lobe infarctions following anterior communicating artery aneurysm
rupture |
title_sort | patient with neurofibromatosis type 1 presenting with bilateral
frontal lobe infarctions following anterior communicating artery aneurysm
rupture |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452425/ https://www.ncbi.nlm.nih.gov/pubmed/31057798 http://dx.doi.org/10.1177/2050313X19841151 |
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