Safety and Immunogenicity of a Heterologous Prime-Boost Ebola Virus Vaccine Regimen in Healthy Adults in the United Kingdom and Senegal

BACKGROUND: The 2014 West African outbreak of Ebola virus disease highlighted the urgent need to develop an effective Ebola vaccine. METHODS: We undertook 2 phase 1 studies assessing safety and immunogenicity of the viral vector modified vaccinia Ankara virus vectored Ebola Zaire vaccine (MVA-EBO-Z)...

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Detalles Bibliográficos
Autores principales: Venkatraman, Navin, Ndiaye, Birahim Pierre, Bowyer, Georgina, Wade, Djibril, Sridhar, Saranya, Wright, Daniel, Powlson, Jonathan, Ndiaye, Ibrahima, Dièye, Siry, Thompson, Craig, Bakhoum, Momar, Morter, Richard, Capone, Stefania, Del Sorbo, Mariarosaria, Jamieson, Sophie, Rampling, Tommy, Datoo, Mehreen, Roberts, Rachel, Poulton, Ian, Griffiths, Oliver, Ballou, W Ripley, Roman, François, Lewis, David J M, Lawrie, Alison, Imoukhuede, Egeruan, Gilbert, Sarah C, Dieye, Tandakha N, Ewer, Katie J, Mboup, Souleymane, Hill, Adrian V S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452431/
https://www.ncbi.nlm.nih.gov/pubmed/30407513
http://dx.doi.org/10.1093/infdis/jiy639

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