Hsp90 Inhibitor SNX-2112 Enhances TRAIL-Induced Apoptosis of Human Cervical Cancer Cells via the ROS-Mediated JNK-p53-Autophagy-DR5 Pathway

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potent cancer cell apoptosis-inducing factor that can induce apoptosis in a variety of cancer cells. However, resistance to TRAIL in cancer cells is a huge obstacle in creating effective TRAIL-targeted clinical therapies. Thus, age...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Liubing, Wang, Yan, Chen, Zui, Fu, Liangshun, Wang, Sheng, Zhang, Xinyue, Zhang, Pengchao, Lu, Xueping, Jie, Huiyang, Li, Manmei, Wang, Yifei, Liu, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452544/
https://www.ncbi.nlm.nih.gov/pubmed/31019655
http://dx.doi.org/10.1155/2019/9675450

Ejemplares similares

Ejemplares similares