Glycoconjugate vaccine using a genetically modified O antigen induces protective antibodies to Francisella tularensis

Francisella tularensis is the causative agent of tularemia, a category A bioterrorism agent. The lipopolysaccharide (LPS) O antigen (OAg) of F. tularensis has been considered for use in a glycoconjugate vaccine, but conjugate vaccines tested so far have failed to confer protection necessary against...

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Detalles Bibliográficos
Autores principales: Stefanetti, Giuseppe, Okan, Nihal, Fink, Avner, Gardner, Erica, Kasper, Dennis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452683/
https://www.ncbi.nlm.nih.gov/pubmed/30872471
http://dx.doi.org/10.1073/pnas.1900144116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452683/
https://www.ncbi.nlm.nih.gov/pubmed/30872471
http://dx.doi.org/10.1073/pnas.1900144116

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