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Glycoconjugate vaccine using a genetically modified O antigen induces protective antibodies to Francisella tularensis
Francisella tularensis is the causative agent of tularemia, a category A bioterrorism agent. The lipopolysaccharide (LPS) O antigen (OAg) of F. tularensis has been considered for use in a glycoconjugate vaccine, but conjugate vaccines tested so far have failed to confer protection necessary against...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452683/ https://www.ncbi.nlm.nih.gov/pubmed/30872471 http://dx.doi.org/10.1073/pnas.1900144116 |