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SIRT1 inhibits hepatocellular carcinoma metastasis by promoting M1 macrophage polarization via NF-κB pathway

BACKGROUND: Tumor-associated macrophages (TAMs) serve as crucial modulators of the complicated interaction between cancer cells and immune microenvironment. Sirtuin 1 (SIRT1) has an impact on immune reactions in cancer progression. Current knowledge of the role of SIRT1 in the regulation of M1-like...

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Detalles Bibliográficos
Autores principales: Zhou, Bei, Yang, Yun, Li, Cuiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452816/
https://www.ncbi.nlm.nih.gov/pubmed/31040695
http://dx.doi.org/10.2147/OTT.S195234