Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium

The compression of brain tissue by a tumour mass is believed to be a major cause of the clinical symptoms seen in patients with brain cancer. However, the biological consequences of these physical stresses on brain tissue are unknown. Here, via imaging studies in patients and by using mouse models o...

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Detalles Bibliográficos
Autores principales: Seano, Giorgio, Nia, Hadi T., Emblem, Kyrre E., Datta, Meenal, Ren, Jun, Krishnan, Shanmugarajan, Kloepper, Jonas, Pinho, Marco C., Ho, William W., Ghosh, Mitrajit, Askoxylakis, Vasileios, Ferraro, Gino B., Riedemann, Lars, Gerstner, Elizabeth R., Batchelor, Tracy T., Wen, Patrick Y., Lin, Nancy U., Grodzinsky, Alan J., Fukumura, Dai, Huang, Peigen, Baish, James W., Padera, Timothy P., Munn, Lance L., Jain, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452896/
https://www.ncbi.nlm.nih.gov/pubmed/30948807
http://dx.doi.org/10.1038/s41551-018-0334-7

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