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Depletion of PD-1-positive cells ameliorates autoimmune disease

Targeted suppression of autoimmune diseases without collateral suppression of normal immunity remains an elusive yet clinically important goal. Targeted blockade of the programmed death-1 receptor (PD-1) — an immune checkpoint factor expressed by activated T cells and B cells — is an efficacious the...

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Detalles Bibliográficos
Autores principales:	Zhao, Peng, Wang, Peng, Dong, Shuyun, Zhou, Zemin, Cao, Yanguang, Yagita, Hideo, He, Xiao, Zheng, Song Guo, Fisher, Simon J., Fujinami, Robert S., Chen, Mingnan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452906/ https://www.ncbi.nlm.nih.gov/pubmed/30952980 http://dx.doi.org/10.1038/s41551-019-0360-0

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