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Heat shock in C. elegans induces downstream of gene transcription and accumulation of double-stranded RNA
We observed that heat shock of Caenorhabditis elegans leads to the formation of nuclear double-stranded RNA (dsRNA) foci, detectable with a dsRNA-specific monoclonal antibody. These foci significantly overlap with nuclear HSF-1 granules. To investigate the molecular mechanism(s) underlying dsRNA foc...
Autores principales: | Melnick, Marko, Gonzales, Patrick, Cabral, Joseph, Allen, Mary A., Dowell, Robin D., Link, Christopher D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453478/ https://www.ncbi.nlm.nih.gov/pubmed/30958820 http://dx.doi.org/10.1371/journal.pone.0206715 |
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