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Whole brain radiotherapy using four-field box technique with tilting baseplate for parotid gland sparing

PURPOSE: The aim of this study is to evaluate the efficacy and feasibility of four-field box whole brain radiotherapy (FB-WBRT) with tilting baseplate by comparing bilateral WBRT (B-WBRT). METHODS AND MATERIALS: Between March 2016 and September 2018, 20 patients with brain metastases underwent WBRT...

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Autores principales: Park, Jaehyeon, Yea, Ji Woon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Radiation Oncology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453806/
https://www.ncbi.nlm.nih.gov/pubmed/30947477
http://dx.doi.org/10.3857/roj.2019.00059
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author Park, Jaehyeon
Yea, Ji Woon
author_facet Park, Jaehyeon
Yea, Ji Woon
author_sort Park, Jaehyeon
collection PubMed
description PURPOSE: The aim of this study is to evaluate the efficacy and feasibility of four-field box whole brain radiotherapy (FB-WBRT) with tilting baseplate by comparing bilateral WBRT (B-WBRT). METHODS AND MATERIALS: Between March 2016 and September 2018, 20 patients with brain metastases underwent WBRT using the four-field box technique. WBRT is performed with a dose of 30 Gy in 10 fractions daily. Two computed tomography simulations per person were performed. One was in the traditional supine position for B-WBRT and the other by applying the tilting acrylic supine baseplate to elevate the head by 40° for FB-WBRT. The B-WBRT used the field-in-field technique, which is the most commonly used method in our institution. The FB-WBRT comprised anterior, posterior, and bilateral beams. A wedge was applied in anterior and posterior fields to compensate for skull convexity. RESULTS: The average of Dmean of both parotid glands was 10.2 Gy (range, 3.8 to 17.8 Gy) in B-WBRT and 5.4 Gy (range, 2.0 to 11.7 Gy) in FB-WBRT (p < 0.05). Compared to B-WBRT, FB-WBRT reduced the mean dose of the right and left parotid glands from 10.1 Gy to 4.9 Gy and from 10.4 Gy to 5.8 Gy, respectively (p < 0.05). Further, V(5), V(10), V(15), V20, and V(25) for the parotid gland decreased significantly in FB-WBRT (p < 0.05). The Dmax and Dmean of lens decreased according to the dose-volume histogram. CONCLUSION: Compared to B-WBRT, FB-WBRT with a tilting baseplate is a simple and effective method that takes feature of noncoplanar beam to protect the parotid gland.
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spelling pubmed-64538062019-04-19 Whole brain radiotherapy using four-field box technique with tilting baseplate for parotid gland sparing Park, Jaehyeon Yea, Ji Woon Radiat Oncol J Original Article PURPOSE: The aim of this study is to evaluate the efficacy and feasibility of four-field box whole brain radiotherapy (FB-WBRT) with tilting baseplate by comparing bilateral WBRT (B-WBRT). METHODS AND MATERIALS: Between March 2016 and September 2018, 20 patients with brain metastases underwent WBRT using the four-field box technique. WBRT is performed with a dose of 30 Gy in 10 fractions daily. Two computed tomography simulations per person were performed. One was in the traditional supine position for B-WBRT and the other by applying the tilting acrylic supine baseplate to elevate the head by 40° for FB-WBRT. The B-WBRT used the field-in-field technique, which is the most commonly used method in our institution. The FB-WBRT comprised anterior, posterior, and bilateral beams. A wedge was applied in anterior and posterior fields to compensate for skull convexity. RESULTS: The average of Dmean of both parotid glands was 10.2 Gy (range, 3.8 to 17.8 Gy) in B-WBRT and 5.4 Gy (range, 2.0 to 11.7 Gy) in FB-WBRT (p < 0.05). Compared to B-WBRT, FB-WBRT reduced the mean dose of the right and left parotid glands from 10.1 Gy to 4.9 Gy and from 10.4 Gy to 5.8 Gy, respectively (p < 0.05). Further, V(5), V(10), V(15), V20, and V(25) for the parotid gland decreased significantly in FB-WBRT (p < 0.05). The Dmax and Dmean of lens decreased according to the dose-volume histogram. CONCLUSION: Compared to B-WBRT, FB-WBRT with a tilting baseplate is a simple and effective method that takes feature of noncoplanar beam to protect the parotid gland. The Korean Society for Radiation Oncology 2019-03 2019-03-31 /pmc/articles/PMC6453806/ /pubmed/30947477 http://dx.doi.org/10.3857/roj.2019.00059 Text en Copyright © 2019 The Korean Society for Radiation Oncology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Park, Jaehyeon
Yea, Ji Woon
Whole brain radiotherapy using four-field box technique with tilting baseplate for parotid gland sparing
title Whole brain radiotherapy using four-field box technique with tilting baseplate for parotid gland sparing
title_full Whole brain radiotherapy using four-field box technique with tilting baseplate for parotid gland sparing
title_fullStr Whole brain radiotherapy using four-field box technique with tilting baseplate for parotid gland sparing
title_full_unstemmed Whole brain radiotherapy using four-field box technique with tilting baseplate for parotid gland sparing
title_short Whole brain radiotherapy using four-field box technique with tilting baseplate for parotid gland sparing
title_sort whole brain radiotherapy using four-field box technique with tilting baseplate for parotid gland sparing
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453806/
https://www.ncbi.nlm.nih.gov/pubmed/30947477
http://dx.doi.org/10.3857/roj.2019.00059
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