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EGFR Mutations in Cell-free Plasma DNA from Patients with Advanced Lung Adenocarcinoma: Improved Detection by Droplet Digital PCR

BACKGROUND: Analysis of cell-free DNA from blood could provide an alternative method for identifying genomic changes in the tumors of patients with advanced lung adenocarcinoma. OBJECTIVE: We compared the performance of droplet digital PCR (ddPCR) and Cobas(®) EGFR Mutation Test v2 (Cobas) for detec...

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Detalles Bibliográficos
Autores principales: Buder, Anna, Setinek, Ulrike, Hochmair, Maximilian J., Schwab, Sophia, Kirchbacher, Klaus, Keck, Andrea, Burghuber, Otto C., Pirker, Robert, Filipits, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453866/
https://www.ncbi.nlm.nih.gov/pubmed/30810887
http://dx.doi.org/10.1007/s11523-019-00623-x