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Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age

In advanced age, some individuals maintain a stable cognitive trajectory while others experience a rapid decline. Such variation in cognitive trajectory is only partially explained by traditional neurodegenerative pathologies. Hence, to identify new processes underlying variation in cognitive trajec...

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Detalles Bibliográficos
Autores principales: Wingo, Aliza P., Dammer, Eric B., Breen, Michael S., Logsdon, Benjamin A., Duong, Duc M., Troncosco, Juan C., Thambisetty, Madhav, Beach, Thomas G., Serrano, Geidy E., Reiman, Eric M., Caselli, Richard J., Lah, James J., Seyfried, Nicholas T., Levey, Allan I., Wingo, Thomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453881/
https://www.ncbi.nlm.nih.gov/pubmed/30962425
http://dx.doi.org/10.1038/s41467-019-09613-z