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Surfaceome interrogation using an RNA-seq approach highlights leukemia initiating cell biomarkers in an LMO2 T cell transgenic model

The surfaceome is critical because surface proteins provide a gateway for internal signals and transfer of molecules into cells, and surfaceome differences can influence therapy response. We have used a surfaceome analysis method, based on comparing RNA-seq data between normal and abnormal cells (Su...

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Detalles Bibliográficos
Autores principales: Pais, Helio, Ruggero, Katia, Zhang, Jing, Al-Assar, Osama, Bery, Nicolas, Bhuller, Ravneet, Weston, Victoria, Kearns, Pamela R., Mecucci, Cristina, Miller, Ami, Rabbitts, Terence H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453905/
https://www.ncbi.nlm.nih.gov/pubmed/30962539
http://dx.doi.org/10.1038/s41598-019-42214-w