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Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting

Caloric restriction and intermittent fasting are emerging therapeutic strategies against obesity, insulin resistance and their complications. However, the effectors that drive this response are not completely defined. Here we identify arginase 2 (Arg2) as a fasting-induced hepatocyte factor that pro...

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Detalles Bibliográficos
Autores principales: Zhang, Yiming, Higgins, Cassandra B., Fortune, Hannah M., Chen, Phillip, Stothard, Alicyn I., Mayer, Allyson L., Swarts, Benjamin M., DeBosch, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453920/
https://www.ncbi.nlm.nih.gov/pubmed/30962478
http://dx.doi.org/10.1038/s41467-019-09642-8