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Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting
Caloric restriction and intermittent fasting are emerging therapeutic strategies against obesity, insulin resistance and their complications. However, the effectors that drive this response are not completely defined. Here we identify arginase 2 (Arg2) as a fasting-induced hepatocyte factor that pro...
Autores principales: | Zhang, Yiming, Higgins, Cassandra B., Fortune, Hannah M., Chen, Phillip, Stothard, Alicyn I., Mayer, Allyson L., Swarts, Benjamin M., DeBosch, Brian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453920/ https://www.ncbi.nlm.nih.gov/pubmed/30962478 http://dx.doi.org/10.1038/s41467-019-09642-8 |
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