Significance of the Tks4 scaffold protein in bone tissue homeostasis

The main driver of osteoporosis is an imbalance between bone resorption and formation. The pathogenesis of osteoporosis has also been connected to genetic alterations in key osteogenic factors and dysfunction of bone marrow mesenchymal stem/stromal cells (BM-MSCs). Tks4 (encoded by the Sh3pxd2b gene...

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Detalles Bibliográficos
Autores principales: Vas, Virag, Kovács, Tamás, Körmendi, Szandra, Bródy, Andrea, Kudlik, Gyöngyi, Szeder, Bálint, Mező, Diána, Kállai, Dóra, Koprivanacz, Kitti, Merő, Balázs L., Dülk, Metta, Tóvári, József, Vajdovich, Péter, Şenel, Ş. Neslihan, Özcan, Ilknur, Helyes, Zsuzsanna, Dobó-Nagy, Csaba, Buday, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453952/
https://www.ncbi.nlm.nih.gov/pubmed/30962481
http://dx.doi.org/10.1038/s41598-019-42250-6

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