Cargando…

Oxytocin Receptor Antagonists, Atosiban and Nolasiban, Inhibit Prostaglandin F(2α)-induced Contractions and Inflammatory Responses in Human Myometrium

Oxytocin receptor antagonists (OTR-A) have been developed as tocolytics for the management of preterm labour due to the significant role of oxytocin (OT) in the onset of both term and preterm labour. Similar to OT, prostaglandins (PGs) play key roles in myometrial contractility and cervical ripening...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Sung Hye, Riaposova, Lucia, Ahmed, Hauwa, Pohl, Oliver, Chollet, André, Gotteland, Jean-Pierre, Hanyaloglu, Aylin, Bennett, Phillip R., Terzidou, Vasso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453954/ https://www.ncbi.nlm.nih.gov/pubmed/30962532 http://dx.doi.org/10.1038/s41598-019-42181-2

Ejemplares similares

Differential Effects of Oxytocin Receptor Antagonists, Atosiban and Nolasiban, on Oxytocin Receptor–Mediated Signaling in Human Amnion and Myometrium
por: Kim, Sung Hye, et al.
Publicado: (2017)

Prostaglandin F2α requires activation of calcium-dependent signalling to trigger inflammation in human myometrium
por: Riaposova, Lucia, et al.
Publicado: (2023)

Confirmation of the cardiac safety of nolasiban in a randomised cohort of healthy female volunteers
por: Täubel, Jörg, et al.
Publicado: (2021)

Effects of exogenous oxytocin and atosiban antagonist on GABA in different region of brain
por: Thakur, Pratibha, et al.
Publicado: (2019)

Effects of oxytocin and antagonist antidote atosiban on body weight and food intake of female mice, Mus musculus
por: Thakur, Pratibha, et al.
Publicado: (2021)

The oxytocin/vasopressin receptor antagonist atosiban delays the gastric emptying of a semisolid meal compared to saline in human
por: Ohlsson, Bodil, et al.
Publicado: (2006)

Electrophysiological Actions of Oxytocin on the Rabbit Myometrium
por: Kleinhaus, A. L., et al.
Publicado: (1969)

NF-κB regulates a cassette of immune/inflammatory genes in human pregnant myometrium at term
por: Khanjani, Shirin, et al.
Publicado: (2011)

Clinically relevant concentrations of dexmedetomidine may reduce oxytocin-induced myometrium contractions in pregnant rats
por: Kim, Dong Joon, et al.
Publicado: (2020)

The In Vitro Contractile Response of Canine Pregnant Myometrium to Oxytocin and Denaverine Hydrochloride
por: Jungmann, Carolin, et al.
Publicado: (2023)

Management of preterm labor: atosiban or nifedipine?
por: de Heus, Roel, et al.
Publicado: (2010)

Poor Spontaneous and Oxytocin-Stimulated Contractility in Human Myometrium from Postdates Pregnancies
por: Arrowsmith, Sarah, et al.
Publicado: (2012)

The Effect of The Release of Exogenous Nitric Oxide on The Responses of The Pregnant Human Myometrium To Oxytocin*
por: Modzelewska, Beata, et al.
Publicado: (2019)

A New Slow Releasing, H(2)S Generating Compound, GYY4137 Relaxes Spontaneous and Oxytocin-Stimulated Contractions of Human and Rat Pregnant Myometrium
por: Robinson, Hayley, et al.
Publicado: (2012)

Effects of anesthetic agents on contractions of the pregnant rat myometrium in vivo and in vitro
por: Kimizuka, Motonobu, et al.
Publicado: (2020)

Dynamics of T2* and deformation in the placenta and myometrium during pre-labour contractions
por: Hutter, Jana, et al.
Publicado: (2022)

NFκB and AP-1 Drive Human Myometrial IL8 Expression
por: Khanjani, Shirin, et al.
Publicado: (2012)

Hexoprenaline Compared with Atosiban as Tocolytic Treatment for Preterm Labor
por: Kirchhoff, Ebba, et al.
Publicado: (2022)

Non-Cardiogenic Pulmonary Edema Due to Administration of Atosiban
por: Dalkalitsis, Alexandros, et al.
Publicado: (2023)

Influence of oxytocin receptor single nucleotide sequence variants on contractility of human myometrium: an in vitro functional study
por: Füeg, F., et al.
Publicado: (2019)

Clinical Experiences and Mechanism of Action with the Use of Oxytocin Injection at Parturition in Domestic Animals: Effect on the Myometrium and Fetuses
por: Marcet-Rius, Míriam, et al.
Publicado: (2023)

Phasic Phosphorylation of Caldesmon and ERK 1/2 during Contractions in Human Myometrium
por: Paul, Jonathan, et al.
Publicado: (2011)

Characterization of the tissue-level Ca(2+) signals in spontaneously contracting human myometrium
por: Bru-Mercier, Gilles, et al.
Publicado: (2012)

Fine spatiotemporal activity in contracting myometrium revealed by motion-corrected calcium imaging
por: Loftus, Fiona C, et al.
Publicado: (2014)

RAC1 is involved in uterine myometrium contraction in the inflammation-associated preterm birth
por: Diao, Min, et al.
Publicado: (2022)

Critical appraisal and clinical utility of atosiban in the management of preterm labor
por: Sanu, Olaleye, et al.
Publicado: (2010)

Oxidative Stress in Women Treated with Atosiban for Impending Preterm Birth
por: Grzesiak, Mariusz, et al.
Publicado: (2018)

Clearance of oxytocin and its potentially enzyme resistant analogues in the OXT‐receptor compartment of the potassium depolarized rat myometrium
por: Pliska, Vladimir, et al.
Publicado: (2021)

The effect of oxytocin antagonist on uterus in response to exogenous oxytocin.
por: Park, S. H., et al.
Publicado: (2000)

Functional rewiring of G protein-coupled receptor signaling in human labor
por: Walker, Abigail R., et al.
Publicado: (2022)

Atosiban versus betamimetics in the treatment of preterm labour in Germany: an economic evaluation
por: Wex, Jaro, et al.
Publicado: (2009)

Efficacy of atosiban for repeated implantation failure in frozen embryo transfer cycles
por: Li, Xiufang, et al.
Publicado: (2023)

Ghrelin in the human myometrium
por: O'Brien, Margaret, et al.
Publicado: (2010)

The Oxytocin-Oxytocin Receptor System and Its Antagonists as Tocolytic Agents
por: Vrachnis, Nikolaos, et al.
Publicado: (2011)

Atosiban-induced acute pulmonary edema: A rare but severe complication of tocolysis
por: Yang, Zuwei, et al.
Publicado: (2023)

Oxytocin in the Male Reproductive Tract; The Therapeutic Potential of Oxytocin-Agonists and-Antagonists
por: Stadler, Beatrix, et al.
Publicado: (2020)

Endogenous Substances Affecting the Myometrium
por: Kase, Nathan
Publicado: (1967)

Whole Blood Holding Time Prior to Plasma Processing Alters microRNA Expression Profile
por: Kim, Sung Hye, et al.
Publicado: (2022)

Effects of tocolysis with nifedipine or atosiban on child outcome: follow‐up of the APOSTEL III trial
por: van Winden, TMS, et al.
Publicado: (2020)

Tocolysis with nifedipine versus atosiban and perinatal outcome: an individual participant data meta-analysis
por: van Winden, Tijn M. S., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rcjar78uc6f3gv296venntop31