Cargando…

5XFAD Mice Show Early Onset Gap Detection Deficits

Alzheimer's patients show auditory temporal processing deficits very early in disease progression, before the onset of major cognitive impairments. In addition to potentially contributing to speech perception and communication deficits in patients, this also represents a potential early biomark...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaylegian, Katherine, Stebritz, Amanda J., Weible, Aldis P., Wehr, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454034/ https://www.ncbi.nlm.nih.gov/pubmed/31001105 http://dx.doi.org/10.3389/fnagi.2019.00066

Ejemplares similares

Disruption of Early or Late Epochs of Auditory Cortical Activity Impairs Speech Discrimination in Mice
por: O’Sullivan, Conor, et al.
Publicado: (2020)

A Layer 3→5 Circuit in Auditory Cortex That Contributes to Pre-pulse Inhibition of the Acoustic Startle Response
por: Weible, Aldis P., et al.
Publicado: (2020)

Auditory Cortex Contributes to Discrimination of Pure Tones
por: O’Sullivan, Conor, et al.
Publicado: (2019)

Decision Making as a Learned Skill in Mice and Humans
por: Posner, Michael I., et al.
Publicado: (2022)

A genetically identified population of layer 4 neurons in auditory cortex that contributes to pre-pulse inhibition of the acoustic startle response
por: Weible, Aldis P., et al.
Publicado: (2022)

Antenatal Hypoxia Accelerates the Onset of Alzheimer’s Disease Pathology in 5xFAD Mouse Model
por: Shen, Guofang, et al.
Publicado: (2020)

Glial Gap Junction Pathology in the Spinal Cord of the 5xFAD Mouse Model of Early-Onset Alzheimer’s Disease
por: Pechlivanidou, Maria, et al.
Publicado: (2022)

Environmental Enrichment Improves Cognitive Deficits, AD Hallmarks and Epigenetic Alterations Presented in 5xFAD Mouse Model
por: Griñán-Ferré, Christian, et al.
Publicado: (2018)

Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer’s disease
por: Giannoni, Patrizia, et al.
Publicado: (2013)

Increased central auditory gain in 5xFAD Alzheimer’s disease mice as an early biomarker candidate for Alzheimer’s disease diagnosis
por: Na, Daxiang, et al.
Publicado: (2023)

Brain and Retinal Abnormalities in the 5xFAD Mouse Model of Alzheimer's Disease at Early Stages
por: Zhang, Mengrong, et al.
Publicado: (2021)

Corrigendum: Increased central auditory gain in 5xFAD Alzheimer's disease mice as an early biomarker candidate for Alzheimer's disease diagnosis
por: Na, Daxiang, et al.
Publicado: (2023)

Altered Expression of Glial Gap Junction Proteins Cx43, Cx30, and Cx47 in the 5XFAD Model of Alzheimer’s Disease
por: Angeli, Stella, et al.
Publicado: (2020)

The Neuroprotective Beta Amyloid Hexapeptide Core Reverses Deficits in Synaptic Plasticity in the 5xFAD APP/PS1 Mouse Model
por: Forest, Kelly H., et al.
Publicado: (2021)

GLAST Deficiency in Mice Exacerbates Gap Detection Deficits in a Model of Salicylate-Induced Tinnitus
por: Yu, Hong, et al.
Publicado: (2016)

Sleeve Gastrectomy Reduces Glycemia but Does Not Affect Cognitive Impairment in Lean 5xFAD Mice
por: Samuel, Itia, et al.
Publicado: (2022)

Age-dependent microstructure alterations in 5xFAD mice by high-resolution diffusion tensor imaging
por: Maharjan, Surendra, et al.
Publicado: (2022)

Cortical cerebrovascular and metabolic perturbations in the 5xFAD mouse model of Alzheimer’s disease
por: Jullienne, Amandine, et al.
Publicado: (2023)

MT5-MMP Promotes Alzheimer’s Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitro
por: Baranger, Kévin, et al.
Publicado: (2017)

Corrigendum: Age-dependent microstructure alterations in 5xFAD mice by high-resolution diffusion tensor imaging
por: Maharjan, Surendra, et al.
Publicado: (2022)

Salicylate-Induced Hearing Loss and Gap Detection Deficits in Rats
por: Radziwon, Kelly E., et al.
Publicado: (2015)

Early Detection of Cerebral Glucose Uptake Changes in the 5XFAD Mouse
por: I.R, Macdonald, et al.
Publicado: (2014)

1950 MHz radiofrequency electromagnetic fields do not aggravate memory deficits in 5xFAD mice
por: Son, Yeonghoon, et al.
Publicado: (2016)

Retinal Functional and Structural Changes in the 5xFAD Mouse Model of Alzheimer’s Disease
por: Lim, Jeremiah K. H., et al.
Publicado: (2020)

Myeloperoxidase Deficiency Inhibits Cognitive Decline in the 5XFAD Mouse Model of Alzheimer’s Disease
por: Volkman, Rotem, et al.
Publicado: (2019)

Phloroglucinol Attenuates the Cognitive Deficits of the 5XFAD Mouse Model of Alzheimer’s Disease
por: Yang, Eun-Jeong, et al.
Publicado: (2015)

Caffeoylquinic Acids in Centella asiatica Reverse Cognitive Deficits in Male 5XFAD Alzheimer’s Disease Model Mice
por: Matthews, Donald G., et al.
Publicado: (2020)

Pregabalin Treatment does not Affect Amyloid Pathology in 5XFAD Mice
por: Sadleir, Katherine R., et al.
Publicado: (2021)

Traditional Japanese Herbal Medicine Yokukansan Targets Distinct but Overlapping Mechanisms in Aged Mice and in the 5xFAD Mouse Model of Alzheimer’s Disease
por: Kaushik, Rahul, et al.
Publicado: (2018)

Intravenous Injection of PHF-Tau Proteins From Alzheimer Brain Exacerbates Neuroinflammation, Amyloid Beta, and Tau Pathologies in 5XFAD Transgenic Mice
por: Houben, Sarah, et al.
Publicado: (2020)

Molecular Mechanisms for Changing Brain Connectivity in Mice and Humans
por: Voelker, Pascale, et al.
Publicado: (2023)

State transitions in the substantia nigra reticulata predict the onset of motor deficits in models of progressive dopamine depletion in mice
por: Willard, Amanda M, et al.
Publicado: (2019)

Early Detection of Aβ Deposition in the 5xFAD Mouse by Amyloid PET
por: Oh, Se Jong, et al.
Publicado: (2018)

Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study
por: Oblak, Adrian L., et al.
Publicado: (2021)

Selective Regional Loss of Cortical Synapses Lacking Presynaptic Mitochondria in the 5xFAD Mouse Model
por: Seo, Na-young, et al.
Publicado: (2021)

Dexmedetomidine exerts an anti-inflammatory effect via α2 adrenoceptors to alleviate cognitive dysfunction in 5xFAD mice
por: Luo, Su-mei, et al.
Publicado: (2022)

Assessment of neurodegeneration and neuronal loss in aged 5XFAD mice
por: Zhang, Liansheng, et al.
Publicado: (2021)

Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome
por: Hurst, Cheyenne D., et al.
Publicado: (2023)

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody
por: Youmans, Katherine L, et al.
Publicado: (2012)

Differential Involvement of Three Brain Regions during Mouse Skill Learning
por: Weible, Aldis P., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ttkjq7ceth9rbo8pbfjnr9hf24