A Golgi-associated redox switch regulates catalytic activation and cooperative functioning of ST6Gal-I with B4GalT-I

Glycosylation, a common modification of cellular proteins and lipids, is often altered in diseases and pathophysiological states such as hypoxia, yet the underlying molecular causes remain poorly understood. By utilizing lectin microarray glycan profiling, Golgi pH and redox screens, we show here th...

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Detalles Bibliográficos
Autores principales: Hassinen, Antti, Khoder-Agha, Fawzi, Khosrowabadi, Elham, Mennerich, Daniela, Harrus, Deborah, Noel, Maxence, Dimova, Elitsa Y., Glumoff, Tuomo, Harduin-Lepers, Anne, Kietzmann, Thomas, Kellokumpu, Sakari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454061/
https://www.ncbi.nlm.nih.gov/pubmed/30959459
http://dx.doi.org/10.1016/j.redox.2019.101182

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