Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques

Despite the enormous effort in the development of effective vaccines against HIV-1, no vaccine candidate has elicited broadly neutralizing antibodies in humans. Thus, generation of more effective anti-HIV vaccines is critically needed. Here we characterize the immune responses induced by nucleoside-...

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Detalles Bibliográficos
Autores principales: Pardi, Norbert, LaBranche, Celia C., Ferrari, Guido, Cain, Derek W., Tombácz, István, Parks, Robert J., Muramatsu, Hiromi, Mui, Barbara L., Tam, Ying K., Karikó, Katalin, Polacino, Patricia, Barbosa, Christopher J., Madden, Thomas D., Hope, Michael J., Haynes, Barton F., Montefiori, David C., Hu, Shiu-Lok, Weissman, Drew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454128/
https://www.ncbi.nlm.nih.gov/pubmed/30974332
http://dx.doi.org/10.1016/j.omtn.2019.03.003

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